Celastrol CAS 34157-83-0

CAS:34157-83-0

Fomula ya Maselo:C29H38O4

Kulemera kwa Maselo:450.61

EINECS:636-472-5

Mawu ofanana:CELASTROL(SH); CELASTROL; Celastrol (Tripterin); CELASTROL(P)(CHONDE IMBIRANI); (20R)-3-Hydroxy-2-oxo-24-nor-D:A-friedoolean-1(10),3,5,7-tetren-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedela-1(10),3,5,7-tetraene-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedelane-1(10),3,5,7-tetraene-29-oic acidCelasterol

Siyani Uthenga Wanu

Tsatanetsatane wa Zamalonda

Tsitsani

Ma tag a Zamalonda

Kodi Celastrol CAS 34157-83-0 ndi chiyani?

Celastrol sisungunuka m'madzi, imasungunuka mu dimethyl sulfoxide ndi anhydrous ethanol. Imachokera ku zosakaniza zogwira ntchito zotsutsana ndi khansa zomwe zimapezeka m'zomera monga Thunder God Vine ndi South Snake Vine m'banja la Celastraceae. Ndi proteasome inhibitor yogwira ntchito, yatsimikiziridwa kuti imayambitsa apoptosis ya maselo a khansa poletsa ntchito ya proteasome.

Kufotokozera

Chinthu	Kufotokozera
Malo otentha	645.7±55.0 °C (Yonenedweratu)
Kuchulukana	1.2
Malo osungunuka	219-230°C
pKa	4.78±0.70(Yanenedweratu)
λmax	424nm(MeOH)(lit.)
Malo osungiramo zinthu	-20°C

Kugwiritsa ntchito

Celastrol imagwiritsidwa ntchito poyesa/kuzindikira/mankhwala, ndi zina zotero. Zotsatira za mankhwala: Ili ndi mphamvu zotsutsana ndi ma antioxidants, zotsatira zotsutsana ndi khansa, komanso zotsatira zotsutsana ndi rheumatoid. Choletsa proteasome chogwira ntchito, chotsimikizika kuti chimayambitsa apoptosis ya maselo a khansa poletsa ntchito ya proteasome.