SHIKONIN CAS 517-89-5 Shikonine
Krustalo wa singano wofiirira, malo osungunuka 147℃, kuzungulira kwa kuwala αD20=+135°(benzene). Amasungunuka mu phenethyl ether, acetone, chloroform, methanol, ethanol, glycerol, mafuta a nyama ndi ndiwo zamasamba ndi madzi a alkaline, osasungunuka m'madzi. Mtundu umasintha ndi mtengo wa Ph, ndi mtengo wa Ph wa 4-6 kukhala wofiira, mtengo wa Ph wa 8 kukhala wofiirira, ndi mtengo wa Ph wa 10-12 kukhala wabuluu. Kukana bwino kuwala, kukana kutentha ndi kukana okosijeni, kusakhazikika pochepetsa mlingo, komanso utoto wakuda ngati pali ayoni achitsulo. Ali ndi mphamvu inayake yoletsa mabakiteriya.
| CAS | 517-89-5 |
| Mayina Ena | Shikonine |
| Maonekedwe | ufa wofiirira |
| Chiyero | 99% |
| Mtundu | wofiirira |
| Malo Osungirako | Malo Osungirako Ozizira Ouma |
| Phukusi | 25kg/thumba |
| Kugwiritsa ntchito | Chakudya |
(1) Zotsatira za kuchepa kwa shuga m'magazi Chotsitsa cha masamba cha comfrey ndi polysaccharide (A, B, C) cha comfrey chili ndi zotsatira zodziwikiratu za kuchepa kwa shuga m'magazi.
(2) Mphamvu ya bacteriostatic Lithospermum imaletsa kachilombo ka Jingke 68-1 mu vitro, ndipo imaletsa Staphylococcus aureus. Mphamvu ya levoshikinin yoletsa kachilombo ka parainfluenza inaphunziridwa pogwiritsa ntchito njira ya hemagglutination ndi njira ya cytopathic. Zotsatira zake zinasonyeza kuti inali ndi poizoni wochepa mkati mwa kuchuluka komwe kunagwiritsidwa ntchito mu kafukufukuyu, ndipo inali ndi mphamvu zina zoletsa kachilombo ka in vitro komanso kupha mwachindunji kachilombo ka parainfluenza.
(3) Zotsatira pa kugayidwa kwa magazi: Kuika jakisoni m'mimba mwa ziwalo za shikonin (shikonin, acetylshikonin) sikukhudza nthawi yogayidwa kwa magazi, koma kungalepheretse mphamvu ya heparin yoletsa magazi kugayidwa.
(4) Mphamvu yoletsa chotupa. Comfrey extract ili ndi mphamvu yoletsa kupanga DNA kumapeto kwa gawo (gawo la G2) m'maselo a Hela.
(5) Mphamvu yoletsa chotupa Shikonin imaletsa kuchulukana kwa maselo, imalimbikitsa apoptosis ndipo imayambitsa kuletsa kwa maselo m'maselo otetezedwa ndi mankhwala a choriocarcinoma (JAR/MTX) omwe amakula mu vitro. Mayeso akuwonetsa kuti kuchuluka kwa shikonin kumawonjezeka ndi mlingo. Ndipo nthawi yogwira ntchito ikawonjezeka, kuchuluka kwa maselo olimbana ndi mankhwala a choriocarcinoma kumawonjezekanso kwambiri.
(6) Zotsatira pa kutulutsa mahomoni Zotsatira za shikonin pa ntchito ya hypothalamic-pituitary-gonadal axis mwa makoswe achikazi achichepere zasonyeza kuti kuchuluka kwa mahomoni m'magazi mwa gulu la shikonin kunali kotsika kwambiri kuposa omwe ali m'gulu lolamulira loipa, ndipo panalibe kusiyana kwakukulu poyerekeza ndi gulu lolamulira labwino. Izi zikusonyeza kuti shikonin imatha kuletsa ntchito ya hypothalamic-pituitary-gonadal axis mwa makoswe.
(7) Mphamvu ya Antioxidant Ofufuza ena anayeza mphamvu ya shikonin yochotsa poizoni m'thupi kupita ku superoxide radical (O2-) ndi 1,1-diphenyl-2-picrophenhydrazine radical (DPPH), ndi momwe imakhudzira β- - Kuletsa kwa carotene/linoleic acid autoxidation system. Zotsatira zake zinasonyeza kuti shikonin inali ndi mphamvu yamphamvu yochotsera poizoni m'thupi kupita ku DPPH ndi O2-, ndipo inali ndi mphamvu yoletsa poizoni m'thupi kupita ku β-carotene/linoleic acid. Mphamvu yamphamvu ya antioxidant.
25kgs/ng'oma, matani 9/chidebe cha 20'
SHIKONIN-1
SHIKONIN-2
