nkhani

Kuti khungu lizisamalidwa bwino, ndithudi, n'kosavuta kukhala ndi lingaliro linalake la zosakaniza, osati kungolimbikitsa malondawo, komanso zosakaniza za malondawo. Lero, tiyeni tikambirane za "carnosine" ya zosakaniza za mankhwala osamalira khungu.

Kodi 'Carnosine' ndi chiyani?
Carnosine ndi dipeptide yopangidwa ndi beta-alanine ndi L-histidine, yomwe ili ndi kuchuluka kwa minofu ndi ubongo zomwe zimatsekeka. Carnosine ili ndi mphamvu zambiri zoteteza ku ma antioxidants ndipo imatha kuchotsa ma free radicals m'thupi.

Momwe 'carnosine' imagwirira ntchito
Carnosine imatha kulimbitsa chitetezo cha khungu, kusunga unyamata wa maselo mwa kusunga ntchito ya maselo mu gulu lonse la spectrum komanso mikhalidwe ya free radicals, kulimbikitsa kupanga collagen, ndikusunga khungu losalala.

Udindo wa 'carnosine'
Carnosine imatha kulimbitsa chitetezo cha khungu, kusunga unyamata wa maselo mwa kusunga ntchito ya maselo mu gulu lonse la spectrum komanso mikhalidwe ya free radicals, kulimbikitsa kupanga collagen, ndikusunga khungu losalala.L-carnosinendi kapangidwe ka beta-alanine ndi L-histidine kudzera mu ntchito ya carnosine synthase. Carnosine imagwiritsidwa ntchito kwambiri m'magawo azachipatala, chisamaliro chaumoyo, komanso ukhondo chifukwa cha mphamvu zake zotsutsana ndi ma antioxidants, mphamvu zake zochotsa ma free radicals, chelation yokhala ndi zitsulo zosinthika, chitetezo cha mitsempha, kulimbikitsa machiritso a mabala, komanso kuletsa ukalamba.

1. Kugwiritsa ntchito carnosine m'makampani azakudya
Gawo lalikulu la mafuta mu chakudya ndi chisakanizo cha ma glycerides osiyanasiyana amafuta. Chifukwa cha free radical reaction ya unsaturated fatty acid glycerides panthawi yosungira, ma peroxide ndi fungo loipa la aldehydes kapena ma carboxylic acid okhala ndi unyolo waufupi wa kaboni amapangidwa. Chifukwa chake, kudya zakudya zokhala ndi mafuta peroxides kumawonjezera lipid peroxidation m'matupi a anthu ndikuyambitsa matenda osiyanasiyana. Chifukwa chake, butylated hydroxyanisole, dibutylated hydroxytoluene, propyl gallate, ndi zina zotero nthawi zambiri zimagwiritsidwa ntchito pokonza ndi kusunga chakudya kuti apewe mafuta peroxidation, koma mphamvu yawo idzachepa pakutentha kwa chakudya, ndipo ili ndi poizoni winawake. L-carnosine sikuti imangoletsa mafuta ochulukirapo, komanso imagwira ntchito zoteteza kwambiri komanso zosamalira thanzi. Chifukwa chake, L-carnosine ndi antioxidant yamtengo wapatali komanso yoyenera chakudya.
2. Kugwiritsa ntchito carnosine mu mankhwala ndi chisamaliro chaumoyo
(1) Carnosine ndi Antioxidant

Carnosine singagwiritse ntchito kokha atomu ya imidazole ring N ndi peptide bond N atomu pa zotsalira za histidine kuti ichotse ma ayoni achitsulo ndikuletsa kusungunuka kwa mafuta komwe kumachitika chifukwa cha ma ayoni achitsulo, komanso histidine yomwe ili pambali pa unyolo wa carnosine imatha kugwira ma hydroxyl radicals. Imatha kuletsa kusungunuka kwa mafuta komwe kumachitika chifukwa cha ma ayoni osakhala achitsulo. Chifukwa chake, monga chinthu chogwira ntchito zambiri zotsutsana ndi antioxidant, carnosine imatha kuteteza nembanemba ya selo mokhazikika ndipo ndi chinthu chosungunula madzi chomwe chimasungunuka ndi ma free radicals. , imatha kuletsa kusungunuka kwa nembanemba ya selo. Poyerekeza ndi ma antioxidants ena achilengedwe monga VC, carnosine ili ndi mphamvu yolimba yolimbana ndi antioxidant. Kuphatikiza pa kuletsa njira yosungunuka kwa nembanemba ya selo, carnosine imathanso kuletsa machitidwe ena a peroxidation mkati mwa maselo, ndiko kuti, carnosine imatha kuletsa gawo lililonse la kusungunuka kwa oxidation mu unyolo wonse wa peroxidation mu chamoyo. Ntchito ya ma antioxidants monga VC ndikuletsa ma free radicals kuti asalowe m'thupi, ndiko kuti, amangoletsa njira yothira madzi mu nembanemba ya selo, ndipo sangachite chilichonse pa ma free radicals omwe alowa m'selo.
(2) Carnosine ndi zilonda zam'mimba

Chilonda cha m'mimba ndi matenda osatha omwe amayambitsa zilonda padziko lonse lapansi, ndipo zinthu zenizeni zomwe zimayambitsa zilonda sizikudziwika bwino pakadali pano, koma matenda amakhulupirira kuti zinthu zoopsa (monga asidi wa m'mimba, kutulutsa kwa pepsin, matenda a Helicobacter pylori) ndi kupewa kapena maselo. Zimachitika chifukwa cha kusalingana kwa zinthu zoteteza (kutulutsa ma ntchofu, kutulutsa kwa bicarbonate, kupanga prostaglandin). Njira yachilengedwe yotetezera m'mimba ndi iyi: imapanga mucosa wokhuthala wa m'mimba womwe umagwira ntchito ngati chotchinga choteteza maselo omwe ali mu nembanemba. Kutulutsa kosalekeza kwa nembanemba ya mucous kumateteza m'mimba, koma kutulutsa kwambiri kungayambitse zilonda zam'mimba. Kafukufuku wapeza kuti zinc-carnosine yomwe imatengedwa ndi chakudya imatha kupewa zilonda, imatha kusunga bwino umphumphu wa m'mimba ndi njira yake yachilengedwe yotetezera, izi zimachitika chifukwa cha mphamvu ya antioxidant ya carnosine, kukhazikika kwa nembanemba, malamulo. Katundu wa mankhwala a chitetezo chamthupi komanso kukonza minofu. Malinga ndi mayeso azachipatala, atamwa zinc-carnosine kwa milungu isanu ndi itatu, 70% ya odwala omwe adamwa mankhwalawa adawonetsa kusintha kwakukulu, ndipo 65% ya zilonda zam'mimba zidawongoleredwa kudzera mu gastroscopy.
(3) Kulamulira kwa carnosine ndi chitetezo chamthupi

Kuyankha kwa chitetezo chamthupi ndi ntchito ya thupi yomwe imasunga homeostasis ndipo imayendetsedwa ndi zinthu zomwe zimagwira ntchito m'thupi mwa zamoyo. Ma immunomodulators amatanthauza kuchiza matenda amtundu wa matenda omwe amayamba chifukwa cha kusagwira bwino ntchito kwa chitetezo chamthupi, ndipo amagwiritsidwa ntchito kubwezeretsa chitetezo chamthupi, kuletsa kuchepa kwake kosazolowereka kapena kuletsa kuyankha kwake mwachangu. Ma immunomodulators ambiri omwe alipo amapangidwa ndi njira zopangira mankhwala, zomwe zimakhala ndi poizoni komanso zotsatirapo zina. Kafukufuku wasonyeza kuti carnosine ili ndi ntchito yowongolera chitetezo chamthupi, ndipo ndiyo chinthu chokhacho chomwe chimapezeka mpaka pano chowongolera chitetezo chamthupi, ndipo chagwiritsidwa ntchito kwambiri pochiza matenda osiyanasiyana a chitetezo chamthupi ndi matenda omwe amayamba chifukwa cha chitetezo chamthupi chosazolowereka.