nkhani

Kusamalira bwino khungu, ndithudi, sikungalephereke kukhala ndi lingaliro linalake la zosakaniza, osati kupititsa patsogolo mankhwala, komanso zosakaniza za mankhwala. Lero, tiyeni tikambirane za "carnosine" zosakaniza za zinthu zosamalira khungu.

'Carnosine' ndi chiyani
Carnosine ndi dipeptide wopangidwa ndi beta-alanine ndi L-histidine, amene ali okhutira kwambiri mu minofu ndi midadada ubongo. Carnosine ali ndi antioxidant katundu ndipo amatha kuwononga ma free radicals m'thupi.

Momwe 'carnosine' imagwirira ntchito
Carnosine ikhoza kuonjezera kukana kwa khungu, kusunga unyamata wa maselo mwa kusunga ntchito ya maselo mu gulu lonse la spectrum ndi mikhalidwe yaulere, kulimbikitsa kupanga kolajeni, ndikusunga khungu.

Udindo wa 'carnosine'
Carnosine ikhoza kuonjezera kukana kwa khungu, kusunga unyamata wa maselo mwa kusunga ntchito ya maselo mu gulu lonse la spectrum ndi mikhalidwe yaulere, kulimbikitsa kupanga kolajeni, ndikusunga khungu. Mankhwala chikhalidwe chaL-carnosinendi mapangidwe beta-alanine ndi L-histidine mwa zochita za carnosine synthase. Carnosine ali ndi chiyembekezo chogwira ntchito pazamankhwala, chisamaliro chaumoyo, ndi ukhondo chifukwa cha antioxidant, zotsatira zowononga kwambiri, chelation ndi zitsulo zosintha, neuroprotection, kukwezedwa kwa machiritso a bala, ndi anti-kukalamba.

1. Kugwiritsa ntchito carnosine m'makampani azakudya
Chigawo chachikulu cha mafuta mu chakudya ndi osakaniza osiyanasiyana mafuta asidi glycerides. Chifukwa cha machitidwe aulere a unsaturated fatty acid glycerides pakusungidwa, peroxides ndi odorous aldehydes kapena carboxylic acid okhala ndi unyolo waufupi wa carbon amapangidwa. Chifukwa chake, kudya zakudya zomwe zili ndi mafuta a peroxide kumalimbikitsa lipid peroxidation m'matupi a anthu ndikuyambitsa matenda osiyanasiyana. Choncho, butylated hydroxyanisole, dibutylated hydroxytoluene, propyl gallate, etc. amagwiritsidwa ntchito pokonza chakudya ndi kusungirako kuteteza mafuta peroxidation, koma efficacy adzakhala kuchepetsedwa mu Kutentha ndondomeko processing chakudya, ndipo ali ndi kawopsedwe. L-carnosine sangathe kuletsa bwino okosijeni wamafuta, komanso amakhala ndi chitetezo chokwanira komanso ntchito zaumoyo. Chifukwa chake, L-carnosine ndi chakudya chamtengo wapatali komanso choyenera cha antioxidant.
2. Kugwiritsa ntchito carnosine mu mankhwala ndi chisamaliro chaumoyo
(1) Carnosine ndi Antioxidant

Carnosine sangakhoze kokha ntchito imidazole mphete N atomu ndi peptide chomangira N atomu pa histidine zotsalira kuti chelate zitsulo ayoni ndi ziletsa makutidwe ndi okosijeni mafuta chifukwa ayoni zitsulo, komanso histidine pa mbali unyolo wa carnosine amatha analanda hydroxyl ankafuna kusintha zinthu mopitirira. Ikhoza kulepheretsa makutidwe ndi okosijeni amafuta omwe amayamba chifukwa cha ayoni omwe si achitsulo. Chifukwa chake, monga mankhwala ophatikizika a antioxidant, carnosine imatha kuteteza nembanemba ya cell ndipo imasungunuka m'madzi mwaulere. , ingalepheretse peroxidation ya cell membrane. Poyerekeza ndi ma antioxidants ena achilengedwe monga VC, carnosine ili ndi mphamvu yamphamvu ya antioxidant. Kuphatikiza pa kuletsa njira ya peroxidation ya nembanemba ya cell, carnosine imathanso kulepheretsa zochitika zina za intracellular peroxidation, ndiko kuti, carnosine imatha kuletsa gawo lililonse la okosijeni mumtundu wonse wa peroxidation mu chamoyo. Udindo wa ma antioxidants monga VC ndikuletsa ma radicals aulere kuti asalowe mu minofu, ndiye kuti, amatha kuteteza njira yamadzimadzi ya peroxidation ya cell membrane, ndipo sangachite chilichonse kwa ma free radicals omwe alowa mu cell.
(2) Carnosine ndi zilonda zam’mimba

Zilonda zam'mimba ndi matenda omwe amayambitsa zilonda zam'mimba padziko lonse lapansi, ndipo zomwe zimayambitsa zilonda sizidziwika bwino pakadali pano, koma matenda amakhulupirira kuti zinthu zowopsa (monga chapamimba acid, secretion ya pepsin, matenda a Helicobacter pylori) komanso kupewa kapena ma cell kusalinganiza kwa zinthu zoteteza (kutuluka kwa ntchentche, kutulutsa kwa bicarbonate, kupanga prostaglandin). Njira yachilengedwe yoteteza m'mimba ndi: imapanga minyewa yamimba yam'mimba yomwe imagwira ntchito ngati chotchinga choteteza ma cell amkati. Kutulutsa kosalekeza kwa mucous nembanemba kumateteza m'mimba, koma kutulutsa kwambiri kungayambitse zilonda zam'mimba. Kafukufuku apeza kuti nthaka-carnosine anatengedwa ndi chakudya akhoza bwino kuteteza zilonda, akhoza bwino kukhalabe umphumphu wa m'mimba ndi limagwirira ake zachilengedwe zoteteza, izi ndi chifukwa cha antioxidant katundu carnosine, nembanemba kukhazikika, lamulo Pharmacological katundu wa chitetezo ndi kukonza minofu. Malinga ndi mayesero azachipatala, atatha kumwa zinc-carnosine kwa milungu isanu ndi itatu, 70% ya odwala omwe adamwa mankhwalawa adawonetsa kusintha kwakukulu, ndipo 65% ya zilonda zam'mimba zidasinthidwa kudzera mu gastroscopy.
(3) Carnosine ndi chitetezo chamthupi

Kuyankha kwa chitetezo chamthupi ndi ntchito ya thupi yomwe imasunga homeostasis ndipo imayendetsedwa ndi zinthu zomwe zimagwira ntchito mu zamoyo. Ma Immunomodulators amatanthawuza chithandizo chamagulu a matenda omwe amayamba chifukwa cha kufooka kwa chitetezo chamthupi, ndipo amagwiritsidwa ntchito kubwezeretsa kuyankha kwa chitetezo chamthupi, kuletsa kuchepa kwake kwachilendo kapena kupondereza kuyankha kwake mwachangu. Ambiri omwe alipo ma immunomodulators amapangidwa ndi njira zopangira mankhwala, zomwe zimakhala ndi poizoni komanso zoyipa. Kafukufuku wasonyeza kuti carnosine ali ndi immunomodulatory ntchito, ndipo ndi yekhayo physiologically yogwira mankhwala opezeka mpaka pano kwa immunomodulation, ndipo wakhala chimagwiritsidwa ntchito pochiza matenda osiyanasiyana chitetezo cha m'thupi ndi matenda obwera chifukwa chachilendo chitetezo chokwanira.