Metronidazole CAS 443-48-1

CAS:443-48-1

Molecular formula:Chithunzi cha C6H9N3O3

Kulemera kwa Molecular:171.15

EINECS:207-136-1

Mawu ofanana ndi mawu:TIMTEC-BB SBB001486; 1-(2-Hydroxy-1-ethyl) -2-methyl-5-nitroimidazole; 1-(2-hydroxyethyl) -2-methyl-5-nitroimidazole; 1-(beta-Hydroxyethyl) -2-methyl-5-nitroimidazole; 1-(beta-Oxyethyl) -2-methyl-5-nitroimidazole; 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-; 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-; 1-Hydroxyethyl-2-methyl-5-nitroimidazole; 2-(2-Methyl-5-nitro-1H-imidazol-1-yl) ethanol; 2-Methyl-1- (2-hydroxyethyl) -5-nitroimidazole

Siyani Uthenga Wanu

Tsatanetsatane wa Zamalonda

Tsitsani

Zolemba Zamalonda

Kodi Metronidazole CAS 443-48-1 ndi chiyani?

Metronidazole ndi woyera kapena pang'ono wachikasu crystalline kapena crystalline ufa; Pali fungo laling'ono, ndi kukoma kowawa komanso mchere pang'ono. Imasungunuka pang'ono mu ethanol, imasungunuka pang'ono m'madzi kapena chloroform, ndipo imasungunuka pang'ono mu ether. Metronidazole ndi nayitrogeni wokhala ndi heterocyclic pawiri ndi alkalinity ndi otsika madzi solubility. Malinga ndi mfundo ya prodrug, metronidazole imapangidwa kukhala potassium phosphate ester, yomwe imawonjezera kusungunuka kwake m'madzi ndipo imatha kugwiritsidwa ntchito ngati jekeseni.

Kufotokozera

Kanthu	Kufotokozera
Malo otentha	301.12°C (kuyerekeza molakwika)
Kuchulukana	1.3994 (kuyerekeza movutikira)
Malo osungunuka	159-161 °C (kuyatsa)
pKa	pKa 2.62(H2O,t =25±0.2,
Zosungirako	2-8 ° C

Kugwiritsa ntchito

Metronidazole imakhala ndi antibacterial wamphamvu pamabakiteriya ambiri a anaerobic ndipo imagwiritsidwa ntchito pochiza amoebiasis, trichomoniasis, ndi matenda a bakiteriya anaerobic. Amagwiritsidwanso ntchito pochiza vaginal trichomoniasis ndipo akhala akugwiritsidwa ntchito kwa amoebiasis a m'mimba ndi extraintestinal kuyambira 1970. Mphamvu yake ndi yapamwamba, poizoni ndi yochepa, ndipo imagwiritsidwa ntchito kwambiri. Ali ndi zotsatira za mutagenic ndi teratogenic pazoyeserera zanyama.