Madecassic acid yokhala ndi CAS 18449-41-7
Madecassic acid ndi triterpenoid yomwe yapezeka mu C. asiatica ndipo imakhala ndi zochita zosiyanasiyana zamoyo. Imaletsa kupanga nitric oxide (NO) chifukwa cha LPS, prostaglandin E2 (PGE2; Item No. 14010), TNF-α, IL-1β, ndi IL-6 mu macrophages a RAW 264.7 ikagwiritsidwa ntchito pamlingo wa 150 μg/ml. Madecassic acid (0.05 ndi 0.1% muzakudya) imachepetsa kuchuluka kwa fibrinogenin ndi triglycerides m'magazi, komanso kuchuluka kwa mtima ndi impso za reactive oxygen species (ROS), mu mtundu wa mbewa wa matenda a shuga oyambitsidwa ndi streptozotocin (STZ; Item No. 13104). Imachepetsa kukula kwa chotupa mu mtundu wa khansa ya colon ya murine ya CT26 motengera mlingo.
| CAS | 18449-41-7 |
| Mayina | Madecassic acid |
| Maonekedwe | Ufa |
| Chiyero | 98% |
| MF | C30H48O6 |
| Giredi | Chakudya $ Giredi Yachipatala |
| Phukusi | 25kgs/thumba, matani 20/chidebe cha 20' |
| Dzina la Kampani | Unilong |
Madecassic Acid ndi terpenoid yokhala ndi chigoba cha ursane chochokera ku Centella asiatica. Madecassic Acid imasonyeza mphamvu zotsutsana ndi kutupa chifukwa cha iNOS, COX-2, TNF-alpha, IL-1beta, ndi IL-6 inhibition kudzera mu kuchepetsa kuyambitsa kwa NF-kappaB mu maselo a RAW 264.7 macrophage.
25kgs/ng'oma, matani 9/chidebe cha 20'
25kgs/thumba, matani 20/chidebe cha 20'
sodium-dodecylbenzenesulphonate
