Celastrol CAS 34157-83-0

CAS:34157-83-0

Molecular formula:C29H38O4

Kulemera kwa Molecular:450.61

EINECS:636-472-5

Mawu ofanana ndi mawu:CELASTROL(SH); CELASTROL; Celastrol (Tripterin); CELASTROL(P)(CHONDE IYIMBENI); (20R) -3-Hydroxy-2-oxo-24-nor-D:A-friedoolean-1 (10),3,5,7-tetren-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedela-1 (10), 3,5,7-tetraene-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedelane-1(10),3,5,7-tetraene-29-oic acidCelasterol

Siyani Uthenga Wanu

Tsatanetsatane wa Zamalonda

Tsitsani

Zolemba Zamalonda

Celastrol CAS 34157-83-0 ndi chiyani?

Celastrol sisungunuka m'madzi, sungunuka mu dimethyl sulfoxide ndi anhydrous ethanol. Zochokera ku zosakaniza zotsutsana ndi khansa muzomera monga Thunder God Vine ndi South Snake Vine m'banja la Celastraceae. Proteasome inhibitor yogwira mtima, yotsimikiziridwa kuti imayambitsa khansa ya apoptosis mwa kuletsa ntchito ya proteasome.

Kufotokozera

Kanthu	Kufotokozera
Malo otentha	645.7±55.0 °C(Zonenedweratu)
Kuchulukana	1.2
Malo osungunuka	219-230 ° C
pKa	4.78±0.70 (Zonenedweratu)
λ max	424nm(MeOH)(lit.)
Zosungirako	-20 ° C

Kugwiritsa ntchito

Celastrol imagwiritsidwa ntchito pofufuza zokhutira / chizindikiritso / zoyesera zamankhwala, etc. Zotsatira za mankhwala: Zili ndi mphamvu zowononga antioxidant, anti-cancer angiogenesis zotsatira, ndi zotsatira za anti-rheumatoid. Proteasome inhibitor yogwira mtima, yotsimikiziridwa kuti imayambitsa khansa ya apoptosis mwa kuletsa ntchito ya proteasome.