ATP disodium mchere CAS 987-65-5

CAS:987-65-5

Chiyero:99%

Molecular formula:C10H17N5NaO13P3

Kulemera kwa Molecular:531.18

EINECS:213-579-1

Nthawi yosungira:zaka 2

Mawu ofanana ndi mawu:ADENOSINETRIPHOSPHATEDISODIUM; ADENOSINETRIPHOSPHATE,DISODIUMSALT; ADENYLPYROPHOSPHORICACIDDISODIUMSALT; ADENOSINE-5′-TRIPHOSPHATEHYDRATEDISODIUMSALT; ADENOSINE-5′-TRIPHOSPHATENA2-CHELETE; ADENOSINE-5′-TRIPHOSPHORICACID,DISODIUM; ADENOSINE-5′-TRIPHOSPHORICACIDDISODIUMDIHYDROGENSALT; ADENOSINE5′-TRIPHOSPHORICACIDDISODIUMSALT

Siyani Uthenga Wanu

Tsatanetsatane wa Zamalonda

Tsitsani

Zolemba Zamalonda

Kodi mchere wa ATP disodium CAS 987-65-5 ndi chiyani?

Mchere wa ATP disodium ndi metabolite ya adenosine, multifunctional nucleoside triphosphate yomwe imagwiritsidwa ntchito ngati coenzyme pakutengera mphamvu zama cell m'maselo. Imayendetsa mphamvu zamagetsi mkati mwa ma cell kuti metabolism. ATP disodium mchere amagwiritsidwa ntchito popanga ribose-modified deoxyadenosine diphosphate analogi monga P2Y1 receptor ligands.

Kufotokozera

Maonekedwe	ufa woyera kapena wopanda- ufa woyera kapena crystal ufa, hygroscopic.
Tinthu kukula	＞95% amadutsa 80 mauna.
pH	2.5-3.5
Kusungunuka	Zosungunuka m'madzi; osasungunuka mu ethanol ndi ether.
Oder	Oderless
Zomwe zili m'madzi	6.0% ~ 12.0%
Chloride	≤0.05%
Mchere wachitsulo	≤0.001%
Zitsulo zolemera	≤0.001%
Kutsogolera	≤2.0ppm
Arsenic	≤1.0ppm

Kugwiritsa ntchito

1. Ntchito zofufuza za mafakitale ndi zasayansi
(1) Zodzikongoletsera zopangira: zowonjezeredwa kuzinthu zosamalira khungu zoletsa kukalamba, zimatha kusintha khungu komanso kunyezimira poyambitsa kagayidwe kazinthu zama cell.
(2) Zowonjezera zakudya: zomwe zimagwiritsidwa ntchito ngati chowonjezera zakudya muzakumwa zamasewera ndi zakudya zogwira ntchito kuti muwonjezere mphamvu mwachangu.
2. Malo ochiritsira kuchipatala
(1) Matenda a mtima ndi mtima: amagwiritsidwa ntchito pa matenda a mtima, myocarditis, infarction ya myocardial ndi cerebral arteriosclerosis, ndi zina zotero, popititsa patsogolo mphamvu ya myocardial metabolism ndi kukulitsa mitsempha ya mitsempha (kuwonjezeka kwa magazi pafupifupi 30%), kuthetsa zizindikiro za myocardial ischemia. Mwachitsanzo, kwa odwala omwe ali ndi vuto lalikulu la myocardial infarction, ATP disodium imatha kufupikitsa gawo la ST nthawi yakugwa ndikuchepetsa mtengo wapamwamba wa sipekitiramu ya myocardial enzyme.
(2) Matenda a mitsempha ya mitsempha: chithandizo chothandizira cha sequelae cha kukha mwazi kwa ubongo, kuwonongeka kwa ubongo ndi kupweteka kwapang'onopang'ono kwa minofu, ndi kulowa m'magazi a ubongo (permeability ndi za 65%), kulimbikitsa kukonzanso maselo a mitsempha ndi kusinthika kwa mitsempha ya mitsempha, ndikuwongolera kuthamanga kwa mitsempha ya mitsempha.
(3) Matenda a metabolic: Pochiza matenda a chiwindi ndi matenda enaake, ATP disodium imatha kupititsa patsogolo ntchito ya mitochondrial ya hepatocytes, kufulumizitsa kukonza kwa hepatocyte, ndi kuchepetsa milingo ya ALT ndi AST; ilinso ndi chithandizo chothandizira pazovuta za matenda a shuga (monga peripheral neuropathy).
3. Magawo ofunsira omwe akubwera
(1) Njira yoperekera mankhwala osokoneza bongo: ATP disodium ingagwiritsidwe ntchito monga chonyamulira chonyamulira, chophatikizidwa ndi liposomes kapena nanoparticles, kuti akwaniritse kuperekedwa kwa mankhwala omwe akukhudzidwa ndi endocytosis yolandirira. Mwachitsanzo, pochiza chotupa, ma nanomedicine osinthidwa ndi ATP amatha kupititsa patsogolo kupha bwino kwamankhwala a chemotherapy pama cell a khansa.
(2) Chikhalidwe cha ma cell ndi biopharmaceuticals: Monga gawo lofunikira la sing'anga ya chikhalidwe cha maselo, ATP disodium ikhoza kulimbikitsa kukula ndi mapuloteni a CHO maselo, maselo a HEK293, ndi zina zotero, ndipo amagwiritsidwa ntchito kwambiri popanga antibody monoclonal.