Mchere wa disodium wa ATP CAS 987-65-5

CAS:987-65-5

Chiyero:99%

Fomula ya Maselo:C10H17N5NaO13P3

Kulemera kwa Maselo:531.18

EINECS:213-579-1

Nthawi Yosungira:zaka 2

Mawu ofanana:ADENOSINETRIPHOSPHATEDISODIUM; ADENOSINETRIPHOSPHATE,DISODIUMSALT; ADENYLPYROPHOSPHORICACIDDISODIUMSALT; ADENOSINE-5′-TRIPHOSPHATEHYDRATEDISODIUMSALT; ADENOSINE-5′-TRIPHOSPHATENA2-SALT; ADENOSINE-5′-TRIPHOSPHATENA2-SALT; ADENOSINE-5′-TRIPHOSPHORICACIDDISODIUMSALT; ADENOSINE5′-TRIPHOSPHORICACIDDISODIUMSALT

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Tsatanetsatane wa Zamalonda

Tsitsani

Ma tag a Zamalonda

Kodi mchere wa ATP disodium CAS 987-65-5 ndi chiyani?

Mchere wa ATP disodium ndi chinthu chomwe chimapezeka mu adenosine, nucleoside triphosphate yomwe imagwiritsidwa ntchito ngati coenzyme yotumizira mphamvu m'maselo. Imanyamula mphamvu zamakemikolo mkati mwa maselo kuti igwiritsidwe ntchito kagayidwe kachakudya. Mchere wa ATP disodium umagwiritsidwa ntchito popanga ma ribose-modified deoxyadenosine diphosphate analogs monga ma P2Y1 receptor ligands.

Kufotokozera

Maonekedwe	Ufa woyera kapena wopanda ufa woyera kapena ufa wa kristalo, wowoneka bwino.
Kukula kwa tinthu	> 95% imadutsa mu maukonde 80.
pH	2.5～3.5
Kusungunuka	Sungunuka m'madzi; susungunuka mu ethanol ndi ether.
Oder	Oderless
Kuchuluka kwa madzi	6.0%~12.0%
Chloride	≤0.05%
Mchere wachitsulo	≤0.001%
Zitsulo zolemera	≤0.001%
Mtsogoleri	≤2.0ppm
Arsenic	≤1.0ppm

Kugwiritsa ntchito

1. Kugwiritsa ntchito kafukufuku wa mafakitale ndi sayansi
(1) Zipangizo zodzikongoletsera: zikawonjezeredwa ku zinthu zosamalira khungu zoletsa kukalamba, zimatha kukulitsa kusinthasintha kwa khungu ndi kunyezimira mwa kuyambitsa kagayidwe ka mphamvu ya maselo.
(2) Zowonjezera zakudya: zimagwiritsidwa ntchito ngati chowonjezera zakudya m'zakumwa zamasewera ndi zakudya zothandiza kuti zibwezeretse mphamvu mwachangu.
2. Malo ochiritsira matenda
(1) Matenda a mtima: amagwiritsidwa ntchito pochiza matenda a mtima, matenda a mtima, matenda a mtima ndi matenda a mitsempha ya m'magazi, ndi zina zotero, mwa kukonza kagayidwe ka mphamvu ya mtima ndi kukulitsa mitsempha ya mtima (kuwonjezera kuyenda kwa magazi ndi pafupifupi 30%), kuchepetsa zizindikiro za ischemia ya mtima. Mwachitsanzo, mwa odwala omwe ali ndi matenda a mtima, ATP disodium imatha kufupikitsa nthawi yogwa ya ST segment ndikuchepetsa kuchuluka kwa enzyme ya myocardial.
(2) Matenda a mitsempha: chithandizo chothandizira cha zotsatira za kutuluka magazi muubongo, kuwonongeka kwa ubongo ndi kufooka kwa minofu, mwa kulowa mu chotchinga cha magazi-ubongo (kulowa kwa magazi ndi pafupifupi 65%), kulimbikitsa kukonzanso kwa nembanemba ya mitsempha ndi kukonzanso njira za mitsempha, komanso kukonza liwiro la kayendedwe ka mitsempha.
(3) Matenda a kagayidwe kachakudya: Pochiza matenda a chiwindi ndi matenda a chiwindi, ATP disodium imatha kuwonjezera ntchito ya mitochondrial ya ma hepatocytes, kufulumizitsa kukonzanso kwa ma hepatocytes, ndikuchepetsa milingo ya ALT ndi AST; imakhalanso ndi zotsatira zabwino pamavuto a shuga (monga peripheral neuropathy).
3. Madera omwe akutuluka
(1) Njira yoperekera mankhwala yolunjika: ATP disodium ingagwiritsidwe ntchito ngati chosinthira chonyamulira, chophatikizidwa ndi liposomes kapena nanoparticles, kuti ikwaniritse kuperekedwa kwa mankhwala mwachindunji kudzera mu endocytosis yolumikizidwa ndi receptor. Mwachitsanzo, pochiza chotupa, nanomedicines yosinthidwa ndi ATP ingathandize kukonza mphamvu yosankha ya mankhwala a chemotherapy pamaselo a khansa.
(2) Kulima maselo ndi mankhwala achilengedwe: Monga gawo lofunika kwambiri la njira yolima maselo, ATP disodium imatha kulimbikitsa kukula ndi kuwonetsa mapuloteni a maselo a CHO, maselo a HEK293, ndi zina zotero, ndipo imagwiritsidwa ntchito kwambiri popanga ma antibodies a monoclonal.